Dr. Dipl.-Psych. Yunbo Yang

Mail: yangy ~at med.uni-marburg.de

I am a scientific researcher in the cluster project “The adaptive mind” which is founded by the HMWK. My aim is to investigate the neural correlates of anxiety disorders and the neurobiological underpinning of cognitive behavior therapy (CBT) effect on anxiety disorders. Studies on patients with anxiety diesorders, especially with panic disorder with/out Agoraphobia, has been my research focus since 2011, the beginning of my PhD study.

Besides my scientific career, I have also built up my expertise in psychotherapy. I finished postgraduate psychotherapy (behavior therapy) training program of Aus- und Weiterbildungseinrichtung für klinische Verhaltenstherapie e.V. (AWKV) and awarded Approbation (national license as psychological psychotherapist).

Research interests

  • neuropathology of anxiety disorders
  • neural correlates of CBT
  • biological mediater/moderator of psychotherapeutic change
  • neural informed indivialization/personalization of psychotherapy
  • neural correlates of therapeutic interaction, therapeut-patient matching
  • new developments of CBT, such as CBASP, metacognitive therapy, ACT and Schema therapy, and their neural scientific foundation


25.11.2009DAAD-Prize for foreign student
23.07.2012Travel Award, Stiftung Felgenhauer und deutschen Gesellschaft für Neurologie
01.08.2012 – 31.01.2013STIBET-Scholarship, DAAD und Phillips-Universität Marburg
01.01.2013 – 31.03.2015Doctoral Scholarship, Studienstiftung des deutschen Volkes
30.11.2014Poster Prize, Deutschen Gesellschaft der Psychiatrie, Psychotherapie, Psychosomatik und Nervenheilkunde (DGPPN)
07.05.2016Chinese Government Award for Outstanding Self-financed Students Abroad, China Scholarhip Council (CSC)


Yang Y, Lueken U, Richter J, Hamm A, Wittmann A, Konrad C, Ströhle A, Pfleiderer B, Herrmann MJ, Lang T, Lotze M, Deckert J, Arolt V, Wittchen H-U, Straube B, Kircher T (2020). Effect of CBT on Biased Semantic Network in Panic Disorder: A Multicenter fMRI Study using Semantic Priming. Am J Psychiatry IF: 13.655

Kunas, S.L., Hilbert, K., Yang, Y., Richter, J., Hamm, A., Wittmann, A., Ströhle, A., Pfleiderer, B., Martin J. Herrmann, M.J., Lang, T., Lotze, M., Deckert, J., Arolt, V., Wittchen, H.-U., Straube, B., Kircher, T., Gerlach, A.L., & Lueken, U. (accepted). The modulating impact of cigarette smoking on brain structure in panic disorder: a voxel-based morphometry study. Social Cognitive Affective Neuroscience. IF: 3.571

Ridderbusch I.C., Yang, Y., Weber, H., Reif, A., Herterich, S., Ströhle, A., Pfleiderer, B., Arolt, V., Wittchen, H.-U., Lueken, U., Kircher, T., & Straube, B. (accepted). Neural correlates of NOS1 ex1f-VNTR allelic variation in panic disorder and agoraphobia during fear conditioning and extinction in fMRI. NeuroImage: Clinical IF: 3.943

Hollandt, M., Wroblewski, A., Yang, Y., Ridderbusch, I., Kircher, T., Hamm, A.O., Straube, B., & Richter, J. (accepted). Facilitating translational science in anxiety disorders by adjusting extinction training in the laboratory to exposure-based therapy procedures (accepted). Translational Psychiatry. IF: 5.182

Heinig, I., Pittig, A., Richter, J., Hummel, K., Alt, I., Dickhöver, K., Gamer, J., Hollandt, M., Kölkebeck, K., Maenz, A., Tennie, S., Totzeck, C., Yang, Y., Arolt, V., Deckert, J., Domschke, K., Fydrich, T., Hamm, A., Hoyer, J., Kircher, T., Lüken, U., Margraf, J., Neudeck, P., Pauli, P., Rief, W., Schneider, S., Straube, B., Ströhle, A., & Wittchen, H.-U. (2017). Optimising Exposure-Based CBT for Anxiety Disorders via Enhanced Extinction: Design and Methods of a Multicentre Randomised Clinical Trial. International Journal of Methods in Psychiatric Research, 26(2), e1560. https://doi.org/10.1002/mpr.1560

Kunas, S. L., Yang, Y., Straube, B., Kircher, T., Gerlach, A. L., Pfleiderer, B., … Lueken, U. (2018). The impact of depressive comorbidity on neural plasticity following cognitive-behavioral therapy in panic disorder with agoraphobia. Journal of Affective Disorders. https://doi.org/10.1016/J.JAD.2018.11.026

Seeger, F., Yang, Y., Straube, B., Kircher, T., Höfler, M., Wittchen, H.-U., … Lueken, U. (2018). Clinical and Neurofunctional Substrates of Cognitive Behavioral Therapy on Secondary Social Anxiety Disorder in Primary Panic Disorder: A Longitudinal fMRI Study. Psychotherapy and Psychosomatics. https://doi.org/10.1159/000493756

Hommers, L. G., Richter, J., Yang, Y., Raab, A., Baumann, C., Lang, K., … Deckert, J. (2018). A functional genetic variation of SLC6A2 repressor hsa-miR-579-3p upregulates sympathetic noradrenergic processes of fear and anxiety. Translational Psychiatry, 8, 226. https://doi.org/10.1038/s41398-018-0278-4

Yang, Y., Lueken, U., Wittmann, A., Holtz, K., Maslowski, N.I., Herrmann, M.J., Sass, K., Jansen, A., Konrad, C., Ströhle, A., Pfleiderer, B., Lotze, M., Hamm, A., Deckert, J., Arolt, V., Wittchen, H.-U., Kircher, T. & Straube, B. (2016). Neural Correlates of Individual Differences in Anxiety Sensitivity: An fMRI Study using Semantic Priming. Social Cognitive and Affective Neuroscience, 11(8), 1245-1254.

Lueken, U., Straube, B., Yang, Y. B., Hahn, T., Beesdo-Baum, K., Wittchen, H. U., . . . Kircher, T. (2015). Separating depressive comorbidity from panic disorder: A combined functional magnetic resonance imaging and machine learning approach. Journal of Affective Disorders, 184, 182-192.

Yang, Y., Kircher, T., Straube, B. (2015) Neurale Korrelate von Psychotherapie bei Panikstörung. Zeitschrift für Psychiatrie, Psychologie und Psychotherapie, 63, 79-87.

Yang, Y., Kircher, T. & Straube, B. (2014). The neural correlates of exposure based cognitive behavioral therapy: Recent progress in the investigation of patients with panic disorder with agoraphobia. Behaviour Research and Therapy, 62, 88–96.