We suggest that several major mental disorders can be understood as maladaptation of mechanisms controlling stability and transition. Understanding the transitions between episodes and the processes that cause healthy or disordered states to persist is the key to explaining and diagnosing such disorders.

Mechanisms of stability and transition are central to effective action and interaction. We must constantly adjust our motor system to achieve stable, goal-directed interactions with the outside world. Here, we use motor control as a particularly rich system for probing adaptation processes.

The adaptive Mind

One of the most critical challenges facing any organism is to maintain stability in the face of a dynamic and uncertain world. At the same time, successful behavior also rests crucially on our ability to adapt when circumstances fundamentally change.

The Adaptive Mind is a research cluster that brings together scientists from Experimental Psychology, Clinical Psychology and Artificial Intelligence in order to understand how the human mind successfully adapts to changing conditions, and what happens when these adaptive processes fail.

The TNM Lab is specifically involved in


Prof. Dr. Benjamin Straube (PI)

Dr. Yunbo Yang (staff)

Christina Schmitter (staff)

Lydia Riedl (associate)

Dr. Adrian Wroblewski (associate)

Dr. Yifei He (associate)

Ridderbusch, I. C., Wroblewski, A., Yang, Y., Richter, J., Hollandt, M., Hamm, A. O., … Straube, B. (2021). Neural adaptation of cingulate and insular activity during delayed fear extinction: A replicable pattern across assessment sites and repeated measurements. NeuroImage, 118157. https://doi.org/https://doi.org/10.1016/j.neuroimage.2021.118157

Wroblewski, A., Hollandt, M., Yang, Y., Ridderbusch, I. C., Pietzner, A., Szeska, C., Lotze, M., Wittchen, H.-U., Heinig, I., Pittig, A., Arolt, V., Koelkebeck, K., Rothkopf, C. A., Adolph, D., Margraf, J., Lueken, U., Pauli, P., Herrmann, M. J., Winkler, M. H., … Straube, B.*, & Richter, J.* (preprint). Sometimes I feel the fear of uncertainty stinging clear: How Intolerance of Uncertainty and Trait Anxiety impact fear acquisition, extinction and the return of fear. https://doi.org/10.31234/OSF.IO/PM9Z5

Straube, B., Kuehne, H., van Dam, L., Frey, K., van Kemenade, B.M., Kircher, T., & Ried, L. (accepted conference contribution). Speech-gesture mismatch detection in individuals with high vs. low schizotypal traits. International Consortium on Schizotypy Research, ICSR 2022.

Arikan, B. E., Kemenade, B. M. Van, Fiehler, K., Kircher, T., Straube, B., & Drewing, K. (2021). Different contributions of efferent and reafferent feedback to sensorimotor temporal recalibration. Scientific Reports, 1–15. https://doi.org/10.1038/s41598-021-02016-5

Cuevas, P.*, He, Y.*, Steines, M. & Straube, B. (2022). The processing of semantic complexity and co-speech gestures in schizophrenia: a naturalistic, multimodal fMRI study. Schizophrenia Bulletin Open, https://doi.org/10.1093/schizbullopen/sgac026  *contributed equally

Uhlmann, L., Pazen, M., van Kemenade, B., Kircher, T., & Straube, B. (2021). Neural Correlates of Self-other Distinction in Patients with Schizophrenia Spectrum Disorders: The Roles of Agency and Hand Identity. Schizophrenia Bulletin, 1–10. https://doi.org/10.1093/schbul/sbaa186